Search on: OREXIN RECEPTORS 
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Descriptor English:   Orexin Receptors 
Descriptor Spanish:   Receptores de Orexina 
Descriptor Portuguese:   Receptores de Orexina 
Tree Number:   D12.776.543.750.720.600.074
D12.776.543.750.750.555.074
Definition English:   G protein-coupled NEUROPEPTIDE RECEPTORS. These proteins have 7-transmembrane domains and are highly conserved across mammals, with 94% amino acid sequence overlap between humans and rats. Orexin-A and -B or hypocretin-1 and -2 neuropeptides produced in the lateral HYPOTHALAMUS promote arousal or wakefulness through orexin receptors. 
History Note English:   2014 
Allowable Qualifiers English:  
AD administration & dosage AG agonists
AN analysis AI antagonists & inhibitors
BI biosynthesis BL blood
CH chemistry CL classification
DF deficiency DE drug effects
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PH physiology
RE radiation effects TU therapeutic use
UL ultrastructure  
Record Number:   55335 
Unique Identifier:   D064446 

Occurrence in VHL: 		 

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